Abstract: Based reviewing on the study state of the sewage irrigation's effect on the groundwater quality, taking the irrigation area with water polluted by coal mine drainage in Zibo coal districts as a example, the water-rock interaction during the process of polluted water irrigation is studied. The results show that the water-rock interaction, such as dissolution and ion exchange, happens during the irrigation water permeation, and during the first process of the irrigation, the dissolution is major, with the development of the irrigation, the ions exchange is got more and more important. In the first process of the irrigation, the dissolution rate is big, but it is got smaller and smaller with the time of the irrigation, even to zero.