Abstract: Using low-carbon steel sheets as fully grouted bolts, centrifugal model test of homogeneous rock slope was carried out and stress responses of fully grouted bolts were studied. Based on the stress responses of fully grouted bolts from the test and practical deformation and failure law of homogeneous rock slope, the preferred position for single bolt stress monitoring of one homogeneous rock slope was also explored by using finite-difference numerical simulation technology and a suggested local strength reduction method on relaxation region. The results are as follows:deformation and failure of the homogeneous rock slope started at the shear failure at the toe of the slope, earlier and obvious stress response of the bolt close to the toe of the slope will be triggered and the stress growth rate of the bolt will also continue to increase with the deformation and failure development of the slope; the closer the distance between stress monitoring point installed in one bolt and potential sliding surface (plastic deformation zone) of the slope, the earlier the time of the bolt stress response and the larger the bolt stress is. It is suggested that the monitoring bolt be put on the slope with 0.25~0.35 H(H is slope height) from the toe of homogeneous rock slope, and concrete analysis must be done for a concrete problem. Results from this paper can provide some references to some extent for the bolts monitoring work of homogeneous rock slope.